Objectives: This exploratory analysis examined the putative antidepressant effect of Matricaria chamomilla L. (chamomile) extract in subjects with generalized anxiety disorder (GAD) with or without comorbid depression. It was hypothesized that chamomile extract would demonstrate similar anxiolytic activity in both subgroups, but superior antidepressant activity in GAD subjects with comorbid depression. Design: As part of a randomized double-blind placebo-controlled trial of chamomile extract for relapse prevention of GAD, 179 subjects received initial therapy with open-label chamomile extract 1500 mg daily for 8 weeks. Linear mixed-effect models were used to identify clinically meaningful changes in anxiety and depression symptoms between diagnostic subgroups. Settings/Location: The study took place at the University of Pennsylvania in Philadelphia, PA. Subjects: Subjects were ≥18 years old with a primary DSM IV-TR diagnosis of GAD. They were subcategorized into two diagnostic groups: GAD without comorbid depression (n = 100) and GAD with comorbid depression (n = 79). Interventions: Open-label chamomile extract 1500 mg was given daily for 8 weeks. Outcome measures: Generalized anxiety disorder (GAD-7), Hamilton rating scale for anxiety, Beck anxiety inventory, Hamilton rating scale for depression (HRSD), the six-item core HRSD (items 1, 2, 3, 7, 8, and 13), and the Beck depression inventory (BDI). Results: The authors observed similar anxiolytic effects over time in both diagnostic subgroups. However, there was a greater reduction in HRSD core symptom scores (p < 0.023), and a trend level reduction in HRSD total scores (p = 0.14) and in BPI total scores (p = 0.060) in subjects with comorbid depression. Conclusions: M. chamomilla L. may produce clinically meaningful antidepressant effects in addition to its anxiolytic activity in subjects with GAD and comorbid depression. Future controlled trials in subjects with primary major depressive disorder are needed to validate this preliminary observation.
Source
Sleep Strips
A gentle and effective way to support restful sleep. Each fast dissolving strip delivers a calming blend of Valerian extract, Lavender, Chamomile, Hibiscus extract, and Melatonin to help ease stress, improve sleep quality, and support a healthy sleep cycle. Enjoy a smooth raspberry flavor and wake up feeling refreshed and energized.
Perfect for anyone seeking natural, non addictive nighttime support.
Ingredients: Valerian root extract, Lavender extract, Chamomile extract, Hibiscus extract, Melatonin, Pullulan, Cellulose, Raspberry Flavor, Malic acid, Xylitol, Lecithin, Erythritol, Sorbitol Syrup, Medium Chain Triglycerides, Steviol Glycosides
WHO IS SLEEP FOR?
Trouble Falling Asleep
For nights when your mind just won't switch off and you're looking for support as part of your bedtime routine.
Busy, Stressed Minds
For people who want to wind down, relax, and create a calmer nighttime routine.
Better Bedtime Routine
For anyone looking to support healthy sleep patterns with a simple, convenient nighttime ritual.
ENERGY Strips
Sleep Strips
Focus Strips
Gut Health Strips
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Natural Sleep IngredientsTrusted Over Time
Our philosophy is to use gentle, time-tested ingredients that support relaxation and healthy sleep patterns.
VALERIAN ROOT
Natural RelaxationSupports calmness and helps the body unwind, making it easier to transition into restful sleep.
CHAMOMILE
Nighttime CalmHelps ease tension and promotes a sense of calm, supporting a smoother bedtime routine.
MELATONIN
Sleep Wake BalanceSupports the body’s natural sleep-wake cycle, helping promote deeper and more consistent sleep.
LAVENDER
Calming Nighttime SupportKnown for its soothing properties, lavender helps promote relaxation and ease stress before bedtime.
HIBISCUS
Botanical BalanceProvides gentle plant based support that complements relaxation focused ingredients for overall nighttime balance.
PULLULAN
Vegan Oral Strip BaseA plant-based ingredient that forms a smooth, quick dissolving strip designed for easy, water free daily use.
Supplements
You Can Trust
Supplement Facts
Servings Per Container: 30
| Ingredient | Amount Per Serving | %Daily Value** |
|---|---|---|
| Melatonin | 1 mg | † |
| Valerian root extract | 50 mg | † |
| Lavender extract | 20 mg | † |
| Chamomile extract | 10 mg | † |
| Hibiscus extract | 10 mg | † |
**Percent Daily Values are based on a 2,000 calorie diet.
Peel. Place. Dissolve.
Peel & Remove
Carefully open the pouch and remove the STRIIPZ oral strip with clean, dry hands.
Place on Your Tongue
Place the strip directly on your tongue and allow it to dissolve completely. No water needed.
Make It a Daily Habit
Take STRIIPZ as directed and stay consistent with your daily wellness routine.
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Manufactured in an FDA-compliant facility
Manufactured in an GMP-compliant facility
Striipz
Gummies
Pills
Fast. Pure. Effective.
waste your time.
